U.S. Federal Route 14 is a east-west highway in La Crosse County. It runs from the La Crosse/Vernon County Line, near Coon Valley, to the Minnesota/Wisconsin State Line, near La Crosse. U.S. Rt. 14 passes through the following town in La Crosse County. La Crosse U.S. Rt. 14 is multi-plexed in La Crosse County. U.S. Rt. 61, throughout La Crosse County.