The Center for Amusing Arts is located at 2438 Commercial St. San Diego, in Logan Heights, right across from the 25th & Commercial Orange Line trolley stop. Trolleys come by every half hour. [schedule]
There's also plenty of street parking in the neighborhood.
When you get close, look for the house with the big neon Technomania Circus sign, and follow the noise and lights into the backyard. Don't be scared. Really, it'll be fine! We're not aliens.