As already mentioned (but it bears repeating), NEVER GIVE UP. Yes, I know you've been rejected by numerous agents and publishers...but so what? This is a very subjective business. As an infamous writing instructor of mine once said, "For every person who hates your book, there are ten people out there who are going to love it." You'll never find them if you throw in the towel.

Regardless of what you've heard, you DO NOT need an agent to sell your work.

Be realistic. Chances are, as good as you might be, the editors at Bantam and Doubleday are probably not going to put you first on their list. Small and mid-list publishers are your most likely targets. If my experience is any indication, they can be an absolute pleasure to work with, affording your project the time and respect it deserves.

Make absolutely certain that your manuscript is the best it can be BEFORE submitting it to an agent or editor. Consider soliciting the advice of friends you may know in the writing business, and, if your wallet allows, hire a freelance editor to read your book. I know, I know--you've heard they're all crooks out to steal your money. They're not. Ask for references. A good editor will offer to look at a portion of your work free of charge, send you a short evaluation, list of all his/her fees up front, and offer to work with you on a payment schedule if need be. For more information on what a professional can do for you, follow the editing link above, or click here.

DO NOT ask a close friend or family member to read your book and tell you what they liked or didn't like about it. Again, be realistic. If they like you, they'll lie and say everything about it was great. If they aren't particularly fond of you, they'll lie and say it was the worst thing they've ever had to suffer through. In either case, you've gained nothing but an enlarged or depleted ego.