U.S. Federal Route 441 runs north-south though Knox County. This is one of the main highways in Downtown Knox County. U.S. Rt. 441 passes through the following towns in Knox County. Halls Crossroads Knoxville U.S. Rt. 441 is multi-plexed in Knoxville. Tennessee State Route 71, in Knox County. Tennessee State Route 33, near Knoxville.
U.S. Rt. 11, at Knoxville. U.S. Rt. 11, at Knoxville. Tennessee State Route 1, at Knoxville. U.S. Rt. 441 intersects the following highways in Knox County. Tennessee State Route 170, near Clinton. Tennessee State Route 131, at Halls Crossroads. Tennessee State Route 33, near Halls Crossroads. Tennessee State Route 331, at Knoxville. Interstate 640, at Knoxville. U.S. Rt. 25W, at Knoxville. Tennessee State Route 9, at Knoxville. Tennessee State Route 158, at Knoxville. U.S. Rt. 11E, at Knoxville. U.S. Rt. 70, at Knoxville. Tennessee State Route 1, at Knoxville. Tennessee State Route 62, at Knoxville. Tennessee State Route 33, at Knoxville. Tennessee State Route 168, near Knoxville.
