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ACTIVASE (Alteplase, t-PA) THERAPY FOR ACUTE ISCHEMIC STROKE

Enter Patient Weight: lbs

  • Must start Activase therapy within 3 hours after onset of symptoms.
  • Must exclude intracranial hemorrhage within these 3 hours.
  • Total Dose should not exceed 90mg.
  • The recommended dose is 0.9 mg/kg (not to exceed 90 mg total dose) infused over 60 minutes with 10% of the total dose administered as an initial intravenous bolus over 1 minute.
Actual Body Weight (ABW):
kg
Recommended Total Dose (0.9mg/kg but not exceed 90mg):
mg

Remove and waste mg from a mg vial of Activase. The remainder of the Activase vial is mg total dose.

Bolus Dose: Use a syringe to withdraw mg (10% of the total dose) from the Activase vial and administer IV push over 1 minute.

Infusion: Infuse the remaining mg (90% of the total dose) from the Activase vial* intravenously over 1 hour.

(*) For 50 mg vials - Using a polyvinyl chloride bag or glass vial to administer. For 100 mg vial - Hang the Activase vial from the plastic molded capping attached to the bottom of the vial.

Please email to Khanh D. Luong for comments, suggestions, or error-reporting.