Nail Patella Syndrome (also called Fong's Disease,
Hereditary Onycho-Osteodysplasia ['HOOD'] is characterized by several typical
abnormalities of the arms and legs as well as kidney disease and glaucoma. It has
been recognized as a hereditary condition for over 100 years and is inherited in an
autosomal dominant manner. That is, the risk of transmission is 50% per pregnancy,
irrespective of gender (just like flipping a coin). Approximately 20% of cases are
sporadic, being the result of a new mutation. The incidence is approximately 1 in
50,000 and occurs throughout the world in all ethnic groups.
What is the
purpose of this website?
Nail Patella
Syndrome is a complex condition that varies greatly between each individual. The
purpose of the website is to provide information to each specialist field of medicine so
that they may recognize those with NPS, as well as to provide contact personnel should
further information be needed in the care of those diagnosed. In addition, this
website hopes to provide information to the general public so that people who are just
discovering that they have NPS have a place to go for information.
Orthopedics,
Nephrology, Ophthalmology and Genetics have been highlighted as these are the specialist
fields of medicine commonly associated with NPS. There are many other areas that should be
included, for example Rheumatology, but for the moment we should concentrate on the four
mentioned above. Please visit the Medical Involvement page for a more in depth look
at each area.
DISCLAIMER: These materials are for informational purposes only, and are intended to
provide you with reliable and timely health information. It is not our aim to provide
health advice or counseling, which should be sought from a licensed health care
practitioner or health care organization.
