Department of Chemical Biology and Therapeutics,
St Jude Children's Research Hospital,,
332 North lauderdale Street,,
Memphis TN 38105 U.S.A.
Tel: +1-901-495-5871
Fax: +1-901-495-5715
WWW: http://www.stjude.org
Ph. D. (Pharmaceutical Sciences) 2001
University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014 India
M. Pharm. (Pharmaceutical Chemistry) 1996
UIPS, PU, Chandigarh
B. Pharm. 1994
UIPS, PU, Chandigarh
Professional Experience
August 2006-to present: Postdoctoral Research Associate, St Jude Children's Research Hospital, Memphis TN, U.S.A.
April 2002-May2006 :Postdoctoral Fellow, National Health Research Institutes, Taipei, Taiwan
October 2000 to March 2002: Lecturer, Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar 143 005 India
April 2000 to October 2000: Fellow, International Centre for Science and High Technology (UNIDO), Trieste 34012 Italy
October 1996 to March 2000: Senior Research Fellow, Regional Research Laboratory (CSIR), Jammu 18001 India
Research Interests
New Drug Discovery, Design and Synthesis of small drug like molecules.
I am presently a member of Dr. Naoaki Fujii's Chemical Biology group. I am working on novel anticancer agents targeted at pediatric cancers.
I worked in Dr. Hsing-Pang Hsieh's lab at Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Taiwan from April 2002 to May 2006. The work focused on designing and synthesis of novel antidiabetic and anticancer compounds.
I did my Ph.D. under the supervision of Prof. V.K. Kapoor and Dr. K. L. Dhar on thesis entitled : A. CHEMICAL INVESTIGATIONS OF PIPER SPP. AND KOELPINIA LINEARIS PALL.B. SYNTHETIC MODIFICATIONS OF VASICINE, AN ALKALOID FROM ADHATODA VASICA NEES. FOR SAR STUDIES
Work experience
More than six years Research Experience in various labs in India and abroad and one and half years teaching experience to Undergraduate and Postgraduate classes at University level. Multistep synthesis of small molecules with an aim to discover new drugs. Resolution of Racemic drugs with the help of enzymes, as well as asymmetric synthesis. Determination of the enantiomeric excess of the resolved compounds with help of chiral HPLC and optical rotation. Microwave mediated organic synthesis. Chemical investigation of natural products utilizing chromatographic techniques and spectroscopy as well as classical techniques to identify the isolated compounds. Essential oils evaluation and adulterant detection with the help of GC-MS and NMR and synthesis of aroma chemicals. Standardization of herbal extracts with the help of HPLC and HPTLC. Acquinted with database and pror art search using Delphion, Derwent, SciFinder, DiscoveryGate, Belelstein Crossfire etc. Well versed with interpretation of NMR, MS, IR, UV spectra and handling of instruments such as NMR, LC-MS, HPLC, HPTLC, UV, IR etc.
I belong to scenic town of Mandi situated in centre of  Northern Indian State of Himachal Pradesh in Lower Himalyas. I did my schooling from Sunder Nagar (H.P.).
