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Depression is not
"All in your head."


If you're depressed helpful friends might tell you to “Snap out of it. It's all in your head.” But serious clinical depression can be a very difficult disease to shake off and depression is not just a mental disease – it's also physical.


Major depression is linked to increased levels of a hormone called prostaglandin E2 (PGE2). Why is this so important?

PGE2 is a controlling hormone also linked to a wide variety of diseases and conditions including chronic pain, osteoporosis, suppression of your immune system, many kinds of inflammation and even multiple sclerosis.

Depression could be an early warning these more serious diseases and conditions are developing in your body.

Increased levels of PGE2 also mean decreased levels of PGE2's opposing hormone prostaglandin E1 (PGE1). PGE1 controls the release of the “feel good” hormone serotonin and low levels of serotonin can leave you feeling unhappy and depressed.

The most commonly prescribed drugs for depression work by increasing levels of serotonin in synapses of your brain but is there a natural treatment for depression?




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