Treatment Comparison

Information based on 644 Patient Profiles

Rituxin treatment is not included in this comparison because not enough patients took

this treatment at the time data was entered into the data base

 

 

The way response time calculated is from the start of a series
 of treatment to the start of the next series of treatment.

 

 

 

 Response Times in Years

 

 

 

Treatment

Number of patients

Average response

time

Median

Response

time

Patients

No other treatment

Average response time

ongoing

Median response time

ongoing

Patients requiring 2nd

 series

Average response1st series for patients requiring

2nd series

Median response1st series for patients requiring

2nd series

2CdA

72

1.89

1.74

43

2.03

1.94

29

1.79

1.08

Fludarabine

62

1.68

1.48

45

1.78

1.52

17

1.41

1.00

Chlorambucil

156

2.16

1.42

63

2.50

1.58

93

1.92

1.25

Cytoxan

41

2.48

2.08

22

2.41

2.08

19

2.55

2.08

 

 

 

 

Treatment

Number of patients

taking a combination of the treatment 

Average response

Time

combination of the treatment 

Median

Response

Time

combination of the treatment 

2CdA

13

1.83

1.97

Fludarabine

20

1.34

0.93

Chlorambucil

48

1.62

1.00

Cytoxan

29

1.95

1.55

 

 

 

 

 

 

 

 

 

 

 

 

Ages

 

 

 

Treatment

Average

age

Median

Age

range

Number of patients

2CdA

59.6

59.1

35 to 78

72

Fludarabine

59.7

60.9

35 to 81

62

Chlorambucil

61.2

61.5

34 to 81

156

Cytoxan

58

59.8

32 to 77

41

 

 

 

 

 Blood Test Data

 

 

 

Treatment

Average

IgM

6

 month

reduction

Median

IgM

6

 month

reduction

Average

WBC

6

month

reduction

Median

WBC

6

month

reduction

Average

RBC

6

 month

increase

Median

RBC

6

 month

increase

Average

HGB

6

 month

increase

Median

HGB

6

 month

increase

2CdA

2000

1500

0.9

0.9

0.4

0.0

1.7

2.5

Fludarabine

2481

2250

1.4

1.5

0.2

0.0

2.1

1.9

Chlorambucil

1464

2450

0.9

0.5

0.1

0.0

0.8

0.5

Cytoxan

2140

1500

0.9

0.5

0.1

0.0

2.0

2.0